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The DNA methylation drift of the atherosclerotic aorta increases with lesion progression

BACKGROUND: Atherosclerosis severity-independent alterations in DNA methylation, a reversible and highly regulated DNA modification, have been detected in aortic atheromas, thus supporting the hypothesis that epigenetic mechanisms participate in the pathogenesis of atherosclerosis. One yet unaddress...

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Detalles Bibliográficos
Autores principales: Valencia-Morales, María del Pilar, Zaina, Silvio, Heyn, Holger, Carmona, F Javier, Varol, Nuray, Sayols, Sergi, Condom, Enric, Ramírez-Ruz, José, Gomez, Antonio, Moran, Sebastian, Lund, Gertrud, Rodríguez-Ríos, Dalia, López-González, Gladys, Ramírez-Nava, Magda, de la Rocha, Carmen, Sanchez-Flores, Alejandro, Esteller, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353677/
https://www.ncbi.nlm.nih.gov/pubmed/25881171
http://dx.doi.org/10.1186/s12920-015-0085-1