N-terminal entrance loop of yeast Yps1 and O-glycosylation of substrates are determinant factors controlling the shedding activity of this GPI-anchored endopeptidase

BACKGROUND: S. cerevisiae Yps1 is the prototypical aspartic endopeptidase of the fungal yapsin family. This glycosylphosphatidylinositol (GPI) anchored enzyme was recently shown to be involved in the shedding of the GPI proteins Utr2, Gas1 and itself. It was also proposed to be part of a novel quali...

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Detalles Bibliográficos
Autores principales: Dubé, Alexandre K, Bélanger, Marc, Gagnon-Arsenault, Isabelle, Bourbonnais, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353680/
https://www.ncbi.nlm.nih.gov/pubmed/25886139
http://dx.doi.org/10.1186/s12866-015-0380-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353680/
https://www.ncbi.nlm.nih.gov/pubmed/25886139
http://dx.doi.org/10.1186/s12866-015-0380-1

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