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A proposed definition of rare diseases for China: from the perspective of return on investment in new orphan drugs

A prevalence threshold to define rare diseases is needed for orphan drug designation. Here, we propose a bottom-up approach to defining rare diseases for China, based on the minimum number of patients needed for the industry to make a reasonable profit on a new drug. To obtain this patient populatio...

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Detalles Bibliográficos
Autores principales: Cui, Yazhou, Han, Jinxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353681/
https://www.ncbi.nlm.nih.gov/pubmed/25757391
http://dx.doi.org/10.1186/s13023-015-0241-x