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A proposed definition of rare diseases for China: from the perspective of return on investment in new orphan drugs
A prevalence threshold to define rare diseases is needed for orphan drug designation. Here, we propose a bottom-up approach to defining rare diseases for China, based on the minimum number of patients needed for the industry to make a reasonable profit on a new drug. To obtain this patient populatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353681/ https://www.ncbi.nlm.nih.gov/pubmed/25757391 http://dx.doi.org/10.1186/s13023-015-0241-x |