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Structure of the Vacuolar H(+)-ATPase Rotary Motor Reveals New Mechanistic Insights

Vacuolar H(+)-ATPases are multisubunit complexes that operate with rotary mechanics and are essential for membrane proton transport throughout eukaryotes. Here we report a ∼1 nm resolution reconstruction of a V-ATPase in a different conformational state from that previously reported for a lower-reso...

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Detalles Bibliográficos
Autores principales: Rawson, Shaun, Phillips, Clair, Huss, Markus, Tiburcy, Felix, Wieczorek, Helmut, Trinick, John, Harrison, Michael A., Muench, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353692/
https://www.ncbi.nlm.nih.gov/pubmed/25661654
http://dx.doi.org/10.1016/j.str.2014.12.016