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MASH1/Ascl1a Leads to GAP43 Expression and Axon Regeneration in the Adult CNS

Unlike CNS neurons in adult mammals, neurons in fish and embryonic mammals can regenerate their axons after injury. These divergent regenerative responses are in part mediated by the growth-associated expression of select transcription factors. The basic helix-loop-helix (bHLH) transcription factor,...

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Detalles Bibliográficos
Autores principales: Williams, Ryan R., Venkatesh, Ishwariya, Pearse, Damien D., Udvadia, Ava J., Bunge, Mary Bartlett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353704/
https://www.ncbi.nlm.nih.gov/pubmed/25751153
http://dx.doi.org/10.1371/journal.pone.0118918