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The Cell Cycle Regulator CCDC6 Is a Key Target of RNA-Binding Protein EWS

Genetic translocation of EWSR1 to ETS transcription factor coding region is considered as primary cause for Ewing sarcoma. Previous studies focused on the biology of chimeric transcription factors formed due to this translocation. However, the physiological consequences of heterozygous EWSR1 loss in...

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Detalles Bibliográficos
Autores principales: Duggimpudi, Sujitha, Larsson, Erik, Nabhani, Schafiq, Borkhardt, Arndt, Hoell, Jessica I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353705/
https://www.ncbi.nlm.nih.gov/pubmed/25751255
http://dx.doi.org/10.1371/journal.pone.0119066