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BDNF-TrkB Axis Regulates Migration of the Lateral Line Primordium and Modulates the Maintenance of Mechanoreceptor Progenitors

BDNF and its specialized receptor TrkB are expressed in the developing lateral line system of zebrafish, but their role in this organ is unknown. To tackle this problem in vivo, we used transgenic animals expressing fluorescent markers in different cell types of the lateral line and combined a BDNF...

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Detalles Bibliográficos
Autores principales: Gasanov, Eugene V., Rafieva, Lola M., Korzh, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353718/
https://www.ncbi.nlm.nih.gov/pubmed/25751404
http://dx.doi.org/10.1371/journal.pone.0119711