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Genetic stability of a recombinant adenovirus vaccine vector seed library expressing human papillomavirus type 16 E6 and E7 proteins

The aim of the present study was to understand the genetic stability of a master seed bank (MSB) and a working seed bank (WSB) of an adenovirus vector vaccine expressing the human papillomavirus (HPV) type 16 E6 and E7 fusion proteins (Ad-HPV16E6E7). Microscopic examination and viral infectious effi...

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Detalles Bibliográficos
Autores principales: WU, JIE, CHEN, KE-DA, GAO, MENG, CHEN, GANG, JIN, SU-FENG, ZHUANG, FANG-CHENG, WU, XIAO-HONG, JIANG, YUN-SHUI, LI, JIAN-BO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353792/
https://www.ncbi.nlm.nih.gov/pubmed/25780403
http://dx.doi.org/10.3892/etm.2015.2268