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Postconditioning with simvastatin decreases myocardial injury in rats following acute myocardial ischemia

The aim of the present study was to investigate whether postconditioning with simvastatin attenuated myocardial ischemia reperfusion injury by inhibiting the expression of high mobility group box 1 (HMGB1) in rat myocardium following acute myocardial ischemia. In total, 30 male Sprague-Dawley rats w...

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Detalles Bibliográficos
Autores principales: YAO, HENG-CHEN, YANG, LAN-JU, HAN, QIAN-FENG, WANG, LAN-HUA, WU, LEI, ZHANG, CHUN-YAN, TIAN, KE-LI, ZHANG, MEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353796/
https://www.ncbi.nlm.nih.gov/pubmed/25780404
http://dx.doi.org/10.3892/etm.2015.2273