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Role of high-mobility group box-1 in myocardial ischemia/reperfusion injury and the effect of ethyl pyruvate

High-mobility group box-1 (HMGB1) acts as a proinflammatory cytokine that triggers and amplifies the inflammation cascade following ischemia/reperfusion (I/R). Ethyl pyruvate (EP) has been reported to inhibit HMGB1 release in several I/R models. This study was designed to investigate the potential r...

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Detalles Bibliográficos
Autores principales: LIN, YUNLING, CHEN, LIANGLONG, LI, WEIWEI, FANG, JUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353799/
https://www.ncbi.nlm.nih.gov/pubmed/25780465
http://dx.doi.org/10.3892/etm.2015.2290