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Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients

The overexpression or amplification of the human epidermal growth factor receptor 2 gene (HER2/neu) is associated with high risk of brain metastasis (BM). The identification of patients at highest immediate risk of BM could optimize screening and facilitate interventional trials. We performed gene e...

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Detalles Bibliográficos
Autores principales: Duchnowska, Renata, Jassem, Jacek, Goswami, Chirayu Pankaj, Dundar, Murat, Gökmen-Polar, Yesim, Li, Lang, Woditschka, Stephan, Biernat, Wojciech, Sosińska-Mielcarek, Katarzyna, Czartoryska-Arłukowicz, Bogumiła, Radecka, Barbara, Tomasevic, Zorica, Stępniak, Piotr, Wojdan, Konrad, Sledge, George W., Steeg, Patricia S., Badve, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353882/
https://www.ncbi.nlm.nih.gov/pubmed/25559688
http://dx.doi.org/10.1007/s11060-014-1704-y