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Multiple Regions of Kaposi’s Sarcoma-Associated Herpesvirus ORF59 RNA are Required for Its Expression Mediated by Viral ORF57 and Cellular RBM15

KSHV ORF57 (MTA) promotes RNA stability of ORF59, a viral DNA polymerase processivity factor. Here, we show that the integrity of both ORF59 RNA ends is necessary for ORF57-mediated ORF59 expression and deletion of both 5’ and 3’ regions, or one end region with a central region, of ORF59 RNA prevent...

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Detalles Bibliográficos
Autores principales: Massimelli, Maria Julia, Majerciak, Vladimir, Kang, Jeong-Gu, Liewehr, David J., Steinberg, Seth M., Zheng, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353900/
https://www.ncbi.nlm.nih.gov/pubmed/25690794
http://dx.doi.org/10.3390/v7020496