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Elevated Cytokines, Thrombin and PAI-1 in Severe HCPS Patients Due to Sin Nombre Virus

Sin Nombre Hantavirus (SNV, Bunyaviridae Hantavirus) is a Category A pathogen that causes Hantavirus Cardiopulmonary Syndrome (HCPS) with case fatality ratios generally ranging from 30% to 50%. HCPS is characterized by vascular leakage due to dysregulation of the endothelial barrier function. The lo...

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Detalles Bibliográficos
Autores principales: Bondu, Virginie, Schrader, Ron, Gawinowicz, Mary Ann, McGuire, Paul, Lawrence, Daniel A., Hjelle, Brian, Buranda, Tione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353904/
https://www.ncbi.nlm.nih.gov/pubmed/25674766
http://dx.doi.org/10.3390/v7020559