The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription

Various cellular stresses activate autophagy, which is involved in lysosomal degradation of cytoplasmic materials for maintaining nutrient homeostasis and eliminating harmful components. Here, we show that RNA polymerase I (Pol I) transcription inhibition induces nucleolar disruption and autophagy....

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Detalles Bibliográficos
Autores principales: Katagiri, Naohiro, Kuroda, Takao, Kishimoto, Hiroyuki, Hayashi, Yuki, Kumazawa, Takuya, Kimura, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354046/
https://www.ncbi.nlm.nih.gov/pubmed/25754892
http://dx.doi.org/10.1038/srep08903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354046/
https://www.ncbi.nlm.nih.gov/pubmed/25754892
http://dx.doi.org/10.1038/srep08903

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