Cargando…
Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours
Epithelial cancer constitutes a major clinical challenge and molecular mechanisms underlying the process of tumour initiation are not well understood. Here we demonstrate that hair follicle bulge stem cells (SCs) give rise to well-differentiated sebaceous tumours and show that SCs are not only cruci...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354047/ https://www.ncbi.nlm.nih.gov/pubmed/25608467 http://dx.doi.org/10.1038/ncomms6874 |