Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids

The double-stranded nature of DNA links its replication, transcription and repair to rotational motion and torsional strain. Magnetic tweezers (MT) are a powerful single-molecule technique to apply both forces and torques to individual DNA or RNA molecules. However, conventional MT do not track rota...

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Detalles Bibliográficos
Autores principales: Lipfert, Jan, Wiggin, Matthew, Kerssemakers, Jacob W.J., Pedaci, Francesco, Dekker, Nynke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354108/
https://www.ncbi.nlm.nih.gov/pubmed/21863006
http://dx.doi.org/10.1038/ncomms1450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354108/
https://www.ncbi.nlm.nih.gov/pubmed/21863006
http://dx.doi.org/10.1038/ncomms1450

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