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Freely orbiting magnetic tweezers to directly monitor changes in the twist of nucleic acids
The double-stranded nature of DNA links its replication, transcription and repair to rotational motion and torsional strain. Magnetic tweezers (MT) are a powerful single-molecule technique to apply both forces and torques to individual DNA or RNA molecules. However, conventional MT do not track rota...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354108/ https://www.ncbi.nlm.nih.gov/pubmed/21863006 http://dx.doi.org/10.1038/ncomms1450 |