Glucocorticoids mediate induction of microRNA-708 to suppress ovarian cancer metastasis through targeting Rap1B

Glucocorticoids are widely used in conjunction with chemotherapy for ovarian cancer to prevent hypersensitivity reactions. Here we reveal a novel role for glucocorticoids in the inhibition of ovarian cancer metastasis. Glucocorticoid treatments induce the expression of miR-708, leading to the suppre...

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Detalles Bibliográficos
Autores principales: Lin, Kai-Ti, Yeh, Yu-Ming, Chuang, Chi-Mu, Yang, Scarlett Y., Chang, Jer-Wei, Sun, Shu-Pin, Wang, Yi-Shiang, Chao, Kuan-Chong, Wang, Lu-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354140/
https://www.ncbi.nlm.nih.gov/pubmed/25569036
http://dx.doi.org/10.1038/ncomms6917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354140/
https://www.ncbi.nlm.nih.gov/pubmed/25569036
http://dx.doi.org/10.1038/ncomms6917

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