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Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function
The ability to differentiate genetically modified mouse embryonic stem (ES) cells into functional macrophages provides a potentially attractive resource to study host-pathogen interactions without the need for animal experimentation. This is particularly useful in instances where the gene of interes...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354151/ https://www.ncbi.nlm.nih.gov/pubmed/25752829 http://dx.doi.org/10.1038/srep08908 |