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Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function

The ability to differentiate genetically modified mouse embryonic stem (ES) cells into functional macrophages provides a potentially attractive resource to study host-pathogen interactions without the need for animal experimentation. This is particularly useful in instances where the gene of interes...

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Detalles Bibliográficos
Autores principales:	Yeung, A. T. Y., Hale, C., Xia, J., Tate, P. H., Goulding, D., Keane, J. A., Mukhopadhyay, S., Forrester, L., Billker, O., Skarnes, W. C., Hancock, R. E. W., Dougan, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354151/ https://www.ncbi.nlm.nih.gov/pubmed/25752829 http://dx.doi.org/10.1038/srep08908

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