Deleting maternal Gtl2 leads to growth enhancement and decreased expression of stem cell markers in teratoma

The distal region of mouse chromosome 12 harbors the Dlk1–Dio3 domain, is essential for normal development and encodes maternally expressed noncoding RNAs (ncRNAs), including Gtl2 as well as paternally expressed proteins.Gtl2 works as a tumor suppressor in several types of human cancer cell lines; h...

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Detalles Bibliográficos
Autores principales: TAKAHASHI, Nozomi, YAMAGUCHI, Eito, KAWABATA, Yukiko, KONO, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354225/
https://www.ncbi.nlm.nih.gov/pubmed/25355544
http://dx.doi.org/10.1262/jrd.2014-089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354225/
https://www.ncbi.nlm.nih.gov/pubmed/25355544
http://dx.doi.org/10.1262/jrd.2014-089

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