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Deleting maternal Gtl2 leads to growth enhancement and decreased expression of stem cell markers in teratoma
The distal region of mouse chromosome 12 harbors the Dlk1–Dio3 domain, is essential for normal development and encodes maternally expressed noncoding RNAs (ncRNAs), including Gtl2 as well as paternally expressed proteins.Gtl2 works as a tumor suppressor in several types of human cancer cell lines; h...
Autores principales: | TAKAHASHI, Nozomi, YAMAGUCHI, Eito, KAWABATA, Yukiko, KONO, Tomohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354225/ https://www.ncbi.nlm.nih.gov/pubmed/25355544 http://dx.doi.org/10.1262/jrd.2014-089 |
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