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Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice

Melatonin protects luteinized granulosa cells (GCs) from oxidative stress in the follicle during ovulation. However, it is unclear in which cellular components (e.g., nuclei, mitochondria, or plasma membranes) melatonin works as an antioxidant. GCs from immature (3 wks) ICR mice were incubated with...

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Detalles Bibliográficos
Autores principales: TANABE, Manabu, TAMURA, Hiroshi, TAKETANI, Toshiaki, OKADA, Maki, LEE, Lifa, TAMURA, Isao, MAEKAWA, Ryo, ASADA, Hiromi, YAMAGATA, Yoshiaki, SUGINO, Norihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354229/
https://www.ncbi.nlm.nih.gov/pubmed/25366368
http://dx.doi.org/10.1262/jrd.2014-105