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Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting

Reprogramming of mouse somatic cells into induced pluripotent stem cells (iPSCs) often generates partially reprogrammed iPSCs (pre-iPSCs), low-grade chimera forming iPSCs (lg-iPSCs) and fully reprogrammed, high-grade chimera production competent iPSCs (hg-iPSCs). Lg-iPSC transcriptome analysis revea...

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Detalles Bibliográficos
Autores principales: Xu, Xingbo, Smorag, Lukasz, Nakamura, Toshinobu, Kimura, Tohru, Dressel, Ralf, Fitzner, Antje, Tan, Xiaoying, Linke, Matthias, Zechner, Ulrich, Engel, Wolfgang, Krishna Pantakani, D. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354275/
https://www.ncbi.nlm.nih.gov/pubmed/25613421
http://dx.doi.org/10.1038/ncomms7008