Cargando…

Differential effects of buffer pH on Ca(2+)-induced ROS emission with inhibited mitochondrial complexes I and III

Excessive mitochondrial reactive oxygen species (ROS) emission is a critical component in the etiology of ischemic injury. Complex I and complex III of the electron transport chain are considered the primary sources of ROS emission during cardiac ischemia and reperfusion (IR) injury. Several factors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindsay, Daniel P., Camara, Amadou K. S., Stowe, David F., Lubbe, Ryan, Aldakkak, Mohammed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354303/ https://www.ncbi.nlm.nih.gov/pubmed/25805998 http://dx.doi.org/10.3389/fphys.2015.00058

Ejemplares similares

Slow Ca(2+) Efflux by Ca(2+)/H(+) Exchange in Cardiac Mitochondria Is Modulated by Ca(2+) Re-uptake via MCU, Extra-Mitochondrial pH, and H(+) Pumping by F(O)F(1)-ATPase
por: Haumann, Johan, et al.
Publicado: (2019)

Stretch-induced increase in cardiac contractility is independent of myocyte Ca(2+) while block of stretch channels by streptomycin improves contractility after ischemic stunning
por: Rhodes, Samhita S, et al.
Publicado: (2015)

Mitochondrial Approaches to Protect Against Cardiac Ischemia and Reperfusion Injury
por: Camara, Amadou K. S., et al.
Publicado: (2011)

Total Matrix Ca(2+) Modulates Ca(2+) Efflux via the Ca(2+)/H(+) Exchanger in Cardiac Mitochondria
por: Natarajan, Gayathri K., et al.
Publicado: (2020)

Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris
por: Aldakkak, Mohammed, et al.
Publicado: (2013)

Mitochondrial targets for volatile anesthetics against cardiac ischemia-reperfusion injury
por: Agarwal, Bhawana, et al.
Publicado: (2014)

Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening
por: Mishra, Jyotsna, et al.
Publicado: (2019)

The calcium-ROS-pH triangle and mitochondrial permeability transition: challenges to mimic cardiac ischemia-reperfusion
por: Javadov, Sabzali
Publicado: (2015)

Editorial: Mitochondrial Exchangers and Transporters in Cell Survival and Death
por: Kwok, Wai-Meng, et al.
Publicado: (2021)

Mitochondria: hubs of cellular signaling, energetics and redox balance. A rich, vibrant, and diverse landscape of mitochondrial research
por: Aon, Miguel A., et al.
Publicado: (2015)

Piezo buffers mechanical stress via modulation of intracellular Ca(2+) handling in the Drosophila heart
por: Zechini, Luigi, et al.
Publicado: (2022)

LETM1: A Single Entity With Diverse Impact on Mitochondrial Metabolism and Cellular Signaling
por: Natarajan, Gayathri K., et al.
Publicado: (2021)

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target
por: Camara, Amadou K. S., et al.
Publicado: (2017)

Mitochondrial BK(Ca) channel
por: Balderas, Enrique, et al.
Publicado: (2015)

High pH-Sensitive Store-Operated Ca(2+) Entry Mediated by Ca(2+) Release-Activated Ca(2+) Channels in Rat Odontoblasts
por: Kimura, Maki, et al.
Publicado: (2018)

Physiological Ca(2+) Transients Versus Pathological Steady-State Ca(2+) Elevation, Who Flips the ROS Coin in Skeletal Muscle Mitochondria
por: Li, Ang, et al.
Publicado: (2020)

The buffer capacity of airway epithelial secretions
por: Kim, Dusik, et al.
Publicado: (2014)

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease
por: Scialò, Filippo, et al.
Publicado: (2017)

Nicotine Causes Mitochondrial Dynamics Imbalance and Apoptosis Through ROS Mediated Mitophagy Impairment in Cardiomyocytes
por: Meng, Ting-ting, et al.
Publicado: (2021)

Integrating Ultra-Weak Photon Emission Analysis in Mitochondrial Research
por: Van Wijk, Roeland, et al.
Publicado: (2020)

Social buffering of the stress response: insights from fishes
por: Gilmour, Kathleen M., et al.
Publicado: (2022)

The Mitochondrial Ca(2+) Uptake and the Fine-Tuning of Aerobic Metabolism
por: Gherardi, Gaia, et al.
Publicado: (2020)

Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome
por: Liu, Xiang-Yong, et al.
Publicado: (2018)

Role of AE2 for pH(i) regulation in biliary epithelial cells
por: Concepcion, Axel R., et al.
Publicado: (2014)

Effects of High-Grain Diet With Buffering Agent on the Hepatic Metabolism in Lactating Goats
por: He, Meilin, et al.
Publicado: (2019)

LETM1-Mediated K(+) and Na(+) Homeostasis Regulates Mitochondrial Ca(2+) Efflux
por: Austin, Shane, et al.
Publicado: (2017)

Role of [Ca(2+)](i) and F-actin on mesothelial barrier function
por: Kuwahara, Masayoshi
Publicado: (2014)

Micron-scale voltage and [Ca(2+)](i) imaging in the intact heart
por: Lu, Xiao-long, et al.
Publicado: (2014)

Activation of Casein Kinase II by Gallic Acid Induces BIK–BAX/BAK-Mediated ER Ca(++)-ROS-Dependent Apoptosis of Human Oral Cancer Cells
por: Lin, Meng-Liang, et al.
Publicado: (2017)

Mitochondrial DNA Mutations in Grade II and III Glioma Cell Lines Are Associated with Significant Mitochondrial Dysfunction and Higher Oxidative Stress
por: Soon, Bee Hong, et al.
Publicado: (2017)

In-vivo Imaging of Mitochondrial Depolarization of Myocardium With Positron Emission Tomography and a Proton Gradient Uncoupler
por: Alpert, Nathaniel M., et al.
Publicado: (2020)

Mitochondrial reactive oxygen species (ROS) as signaling molecules of intracellular pathways triggered by the cardiac renin-angiotensin II-aldosterone system (RAAS)
por: De Giusti, V. C., et al.
Publicado: (2013)

Neuronal Redox-Imbalance in Rett Syndrome Affects Mitochondria as Well as Cytosol, and Is Accompanied by Intensified Mitochondrial O(2) Consumption and ROS Release
por: Can, Karolina, et al.
Publicado: (2019)

PPARγ-Independent Side Effects of Thiazolidinediones on Mitochondrial Redox State in Rat Isolated Hearts
por: Riess, Matthias L., et al.
Publicado: (2020)

The effect of pre-exercise alkalosis on lactate/pH regulation and mitochondrial respiration following sprint-interval exercise in humans
por: Thomas, Claire, et al.
Publicado: (2023)

Wnt 3a Protects Myocardial Injury in Elderly Acute Myocardial Infarction by Inhibiting Serum Cystatin C/ROS-Induced Mitochondrial Damage
por: Shen, Jian, et al.
Publicado: (2022)

Pharmacological Modulation of Mitochondrial Ca(2+) Content Regulates Sarcoplasmic Reticulum Ca(2+) Release via Oxidation of the Ryanodine Receptor by Mitochondria-Derived Reactive Oxygen Species
por: Hamilton, Shanna, et al.
Publicado: (2018)

Non-carbonic buffer power of whole blood is increased in experimental metabolic acidosis: An in-vitro study
por: Krbec, Martin, et al.
Publicado: (2022)

Routes of Ca(2+) Shuttling during Ca(2+) Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca(2+) HANDLING AND CYTOSOLIC Ca(2+) BUFFERS
por: Pecze, László, et al.
Publicado: (2015)

Differential Modulation of I(K) and I(Ca,L) Channels in High-Fat Diet-Induced Obese Guinea Pig Atria
por: Martinez-Mateu, Laura, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mns42ra9dfktddj14te6i3td9r