Shikonin Isolated from Lithospermum erythrorhizon Downregulates Proinflammatory Mediators in Lipopolysaccharide-Stimulated BV2 Microglial Cells by Suppressing Crosstalk between Reactive Oxygen Species and NF-κB

According to the expansion of lifespan, neuronal disorder based on inflammation has been social problem. Therefore, we isolated shikonin from Lithospermum erythrorhizon and evaluated anti-inflammatory effects of shikonin in lipopolysaccharide (LSP)-stimulated BV2 microglial cells. Shikonin dose-depe...

Descripción completa

Detalles Bibliográficos
Autores principales: Prasad, Rajapaksha Gedara, Choi, Yung Hyun, Kim, Gi-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354311/
https://www.ncbi.nlm.nih.gov/pubmed/25767678
http://dx.doi.org/10.4062/biomolther.2015.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354311/
https://www.ncbi.nlm.nih.gov/pubmed/25767678
http://dx.doi.org/10.4062/biomolther.2015.006

Ejemplares similares