Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A2*8, *15, and *16 (R456H, P42R, and R377Q)

P450 1A2 is responsible for the metabolism of clinically important drugs and the metabolic activation of environmental chemicals. Genetic variations of P450 1A2 can influence its ability to perform these functions, and thus, this study aimed to characterize the functional significance of three P450...

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Detalles Bibliográficos
Autores principales: Lim, Young-Ran, Kim, In-Hyeok, Han, Songhee, Park, Hyoung-Goo, Ko, Mi-Jung, Chun, Young-Jin, Yun, Chul-Ho, Kim, Donghak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354321/
https://www.ncbi.nlm.nih.gov/pubmed/25767688
http://dx.doi.org/10.4062/biomolther.2015.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354321/
https://www.ncbi.nlm.nih.gov/pubmed/25767688
http://dx.doi.org/10.4062/biomolther.2015.009

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