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Improved Cell-Penetrating Zinc-Finger Nuclease Proteins for Precision Genome Engineering

Safe, efficient, and broadly applicable methods for delivering site-specific nucleases into cells are needed in order for targeted genome editing to reach its full potential for basic research and medicine. We previously reported that zinc-finger nuclease (ZFN) proteins have the innate capacity to c...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Gaj, Thomas, Wallen, Mark C, Barbas, Carlos F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354341/
https://www.ncbi.nlm.nih.gov/pubmed/25756962
http://dx.doi.org/10.1038/mtna.2015.6