Pregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway

Pregnenolone sulfate, an endogenous neurosteroid in the central nervous system, is a positive allosteric modulator of the NMDA receptor, and plays a role in the modulation of learning and memory. Here, we study the actions of pregnenolone sulfate using the dopamine transporter knockout (DAT-KO) mice...

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Detalles Bibliográficos
Autores principales: Wong, P, Sze, Y, Chang, C C R, Lee, J, Zhang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354351/
https://www.ncbi.nlm.nih.gov/pubmed/25781227
http://dx.doi.org/10.1038/tp.2015.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354351/
https://www.ncbi.nlm.nih.gov/pubmed/25781227
http://dx.doi.org/10.1038/tp.2015.21

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