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Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease

Glutamatergic systems play a critical role in cognitive functions and are known to be defective in Alzheimer’s disease (AD) patients. Previous literature has indicated that glial glutamate transporter EAAT2 plays an essential role in cognitive functions and that loss of EAAT2 protein is a common phe...

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Detalles Bibliográficos
Autores principales: Takahashi, Kou, Kong, Qiongman, Lin, Yuchen, Stouffer, Nathan, Schulte, Delanie A., Lai, Liching, Liu, Qibing, Chang, Ling-Chu, Dominguez, Sky, Xing, Xuechao, Cuny, Gregory D., Hodgetts, Kevin J., Glicksman, Marcie A., Lin, Chien-Liang Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354363/
https://www.ncbi.nlm.nih.gov/pubmed/25711212
http://dx.doi.org/10.1084/jem.20140413