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Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease
Glutamatergic systems play a critical role in cognitive functions and are known to be defective in Alzheimer’s disease (AD) patients. Previous literature has indicated that glial glutamate transporter EAAT2 plays an essential role in cognitive functions and that loss of EAAT2 protein is a common phe...
Autores principales: | Takahashi, Kou, Kong, Qiongman, Lin, Yuchen, Stouffer, Nathan, Schulte, Delanie A., Lai, Liching, Liu, Qibing, Chang, Ling-Chu, Dominguez, Sky, Xing, Xuechao, Cuny, Gregory D., Hodgetts, Kevin J., Glicksman, Marcie A., Lin, Chien-Liang Glenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354363/ https://www.ncbi.nlm.nih.gov/pubmed/25711212 http://dx.doi.org/10.1084/jem.20140413 |
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