Targeting IL-17B–IL-17RB signaling with an anti–IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines

Pancreatic cancer has an extremely high mortality rate due to its aggressive metastatic nature. Resolving the underlying mechanisms will be crucial for treatment. Here, we found that overexpression of IL-17B receptor (IL-17RB) strongly correlated with postoperative metastasis and inversely correlate...

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Detalles Bibliográficos
Autores principales: Wu, Heng-Hsiung, Hwang-Verslues, Wendy W., Lee, Wen-Hsin, Huang, Chun-Kai, Wei, Pei-Chi, Chen, Chia-Lin, Shew, Jin-Yuh, Lee, Eva Y.-H.P., Jeng, Yung-Ming, Tien, Yu-Wen, Ma, Che, Lee, Wen-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354366/
https://www.ncbi.nlm.nih.gov/pubmed/25732306
http://dx.doi.org/10.1084/jem.20141702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354366/
https://www.ncbi.nlm.nih.gov/pubmed/25732306
http://dx.doi.org/10.1084/jem.20141702

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