Epithelial NAIPs protect against colonic tumorigenesis

NLR family apoptosis inhibitory proteins (NAIPs) belong to both the Nod-like receptor (NLR) and the inhibitor of apoptosis (IAP) families. NAIPs are known to form an inflammasome with NLRC4, but other in vivo functions remain unexplored. Using mice deficient for all NAIP paralogs (Naip1-6(Δ/Δ)), we...

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Detalles Bibliográficos
Autores principales: Allam, Ramanjaneyulu, Maillard, Michel H., Tardivel, Aubry, Chennupati, Vijaykumar, Bega, Hristina, Yu, Chi Wang, Velin, Dominique, Schneider, Pascal, Maslowski, Kendle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354369/
https://www.ncbi.nlm.nih.gov/pubmed/25732303
http://dx.doi.org/10.1084/jem.20140474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354369/
https://www.ncbi.nlm.nih.gov/pubmed/25732303
http://dx.doi.org/10.1084/jem.20140474

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