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Amoxicillin concentrations in relation to beta-lactamase activity in sputum during exacerbations of chronic obstructive pulmonary disease

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (COPD) are often treated with antibiotics. Theoretically, to be maximally effective, the antibiotic concentration at sites of infection should exceed the minimum inhibitory concentration at which 90% of the growth of potential...

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Detalles Bibliográficos
Autores principales: Brusse-Keizer, Marjolein, VanderValk, Paul, van der Zanden, Rogier W, Nijdam, Lars, van der Palen, Job, Hendrix, Ron, Movig, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354398/
https://www.ncbi.nlm.nih.gov/pubmed/25767383
http://dx.doi.org/10.2147/COPD.S70355