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Amoxicillin concentrations in relation to beta-lactamase activity in sputum during exacerbations of chronic obstructive pulmonary disease
BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (COPD) are often treated with antibiotics. Theoretically, to be maximally effective, the antibiotic concentration at sites of infection should exceed the minimum inhibitory concentration at which 90% of the growth of potential...
Autores principales: | Brusse-Keizer, Marjolein, VanderValk, Paul, van der Zanden, Rogier W, Nijdam, Lars, van der Palen, Job, Hendrix, Ron, Movig, Kris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354398/ https://www.ncbi.nlm.nih.gov/pubmed/25767383 http://dx.doi.org/10.2147/COPD.S70355 |
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