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In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii

Girinimbine is a carbazole alkaloid isolated from the stem bark and root of Murraya koenigii. Here we report that girinimbine is an inhibitor of angiogenic activity both in vitro and in vivo. MTT results showed that girinimbine inhibited proliferation of human umbilical vein endothelial cells, while...

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Detalles Bibliográficos
Autores principales: Iman, Venoos, Karimian, Hamed, Mohan, Syam, Hobani, Yahya Hasan, Noordin, Mohamed Ibrahim, Mustafa, Mohd Rais, Noor, Suzita Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354401/
https://www.ncbi.nlm.nih.gov/pubmed/25767375
http://dx.doi.org/10.2147/DDDT.S71557