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Regulation of the DNA damage response by ubiquitin conjugation

In response to DNA damage, cells activate a highly conserved and complex kinase-based signaling network, commonly referred to as the DNA damage response (DDR), to safeguard genomic integrity. The DDR consists of a set of tightly regulated events, including detection of DNA damage, accumulation of DN...

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Detalles Bibliográficos
Autores principales: Brinkmann, Kerstin, Schell, Michael, Hoppe, Thorsten, Kashkar, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354423/
https://www.ncbi.nlm.nih.gov/pubmed/25806049
http://dx.doi.org/10.3389/fgene.2015.00098