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Regulation of the DNA damage response by ubiquitin conjugation
In response to DNA damage, cells activate a highly conserved and complex kinase-based signaling network, commonly referred to as the DNA damage response (DDR), to safeguard genomic integrity. The DDR consists of a set of tightly regulated events, including detection of DNA damage, accumulation of DN...
Autores principales: | Brinkmann, Kerstin, Schell, Michael, Hoppe, Thorsten, Kashkar, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354423/ https://www.ncbi.nlm.nih.gov/pubmed/25806049 http://dx.doi.org/10.3389/fgene.2015.00098 |
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