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Matrix metalloproteinases in atherosclerosis: role of nitric oxide, hydrogen sulfide, homocysteine, and polymorphisms

Atherosclerosis is an inflammatory process that involves activation of matrix metalloproteinases (MMPs); MMPs degrade collagen and allow for smooth-muscle cell migration within a vessel. Moreover, this begets an accumulation of other cellular material, resulting in occlusion of the vessel and ischem...

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Detalles Bibliográficos
Autores principales: Vacek, Thomas P, Rehman, Shahnaz, Neamtu, Diana, Yu, Shipeng, Givimani, Srikanth, Tyagi, Suresh C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354431/
https://www.ncbi.nlm.nih.gov/pubmed/25767394
http://dx.doi.org/10.2147/VHRM.S68415