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Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase

New agent development, mechanistic understanding, and combinatorial partnerships with known and novel modalities continue to be important in the study of pancreatic cancer and its improved treatment. In this study, known antimetabolite drugs such as gemcitabine (ribonucleotide reductase inhibitor) a...

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Detalles Bibliográficos
Autores principales: Asuncion Valenzuela, Malyn M, Castro, Imilce, Gonda, Amber, Diaz Osterman, Carlos J, Jutzy, Jessica M, Aspe, Jonathan R, Khan, Salma, Neidigh, Jonathan W, Wall, Nathan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354452/
https://www.ncbi.nlm.nih.gov/pubmed/25767396
http://dx.doi.org/10.2147/OTT.S79647