Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons

Therapeutic and mechanistic studies of the presynaptically targeted clostridial neurotoxins (CNTs) have been limited by the need for a scalable, cell-based model that produces functioning synapses and undergoes physiological responses to intoxication. Here we describe a simple and robust method to e...

Descripción completa

Detalles Bibliográficos
Autores principales: Hubbard, Kyle, Beske, Phillip, Lyman, Megan, McNutt, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354605/
https://www.ncbi.nlm.nih.gov/pubmed/25742030
http://dx.doi.org/10.3791/52361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354605/
https://www.ncbi.nlm.nih.gov/pubmed/25742030
http://dx.doi.org/10.3791/52361

Ejemplares similares