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Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons

Therapeutic and mechanistic studies of the presynaptically targeted clostridial neurotoxins (CNTs) have been limited by the need for a scalable, cell-based model that produces functioning synapses and undergoes physiological responses to intoxication. Here we describe a simple and robust method to e...

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Detalles Bibliográficos
Autores principales:	Hubbard, Kyle, Beske, Phillip, Lyman, Megan, McNutt, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354605/ https://www.ncbi.nlm.nih.gov/pubmed/25742030 http://dx.doi.org/10.3791/52361

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