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Four Core Genotypes mouse model: localization of the Sry transgene and bioassay for testicular hormone levels
BACKGROUND: The “four core genotypes” (FCG) mouse model has emerged as a major model testing if sex differences in phenotypes are caused by sex chromosome complement (XX vs. XY) or gonadal hormones or both. The model involves deletion of the testis-determining gene Sry from the Y chromosome and inse...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354741/ https://www.ncbi.nlm.nih.gov/pubmed/25870930 http://dx.doi.org/10.1186/s13104-015-0986-2 |