Four Core Genotypes mouse model: localization of the Sry transgene and bioassay for testicular hormone levels

BACKGROUND: The “four core genotypes” (FCG) mouse model has emerged as a major model testing if sex differences in phenotypes are caused by sex chromosome complement (XX vs. XY) or gonadal hormones or both. The model involves deletion of the testis-determining gene Sry from the Y chromosome and inse...

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Detalles Bibliográficos
Autores principales: Itoh, Yuichiro, Mackie, Ryan, Kampf, Kathy, Domadia, Shelly, Brown, Judith D, O’Neill, Rachel, Arnold, Arthur P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354741/
https://www.ncbi.nlm.nih.gov/pubmed/25870930
http://dx.doi.org/10.1186/s13104-015-0986-2

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