Cargando…
Process development for the production of 15β-hydroxycyproterone acetate using Bacillus megaterium expressing CYP106A2 as whole-cell biocatalyst
BACKGROUND: CYP106A2 from Bacillus megaterium ATCC 13368 was first identified as a regio- and stereoselective 15β-hydroxylase of 3-oxo-∆(4)-steroids. Recently, it was shown that besides 3-oxo-∆(4)-steroids, 3-hydroxy-∆(5)-steroids as well as di- and triterpenes can also serve as substrates for this...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354754/ https://www.ncbi.nlm.nih.gov/pubmed/25890176 http://dx.doi.org/10.1186/s12934-015-0210-z |