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A role for the two-helix finger of the SecA ATPase in protein translocation

An important step in the biosynthesis of many proteins is their partial or complete translocation across the plasma membrane in prokaryotes or the endoplasmic reticulum membrane in eukaryotes (1). In bacteria, secretory proteins are generally translocated after completion of their synthesis by the i...

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Detalles Bibliográficos
Autores principales: Erlandson, Karl J., Miller, Stephanie B. M., Nam, Yunsun, Osborne, Andrew R., Zimmer, Jochen, Rapoport, Tom A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354775/
https://www.ncbi.nlm.nih.gov/pubmed/18923526
http://dx.doi.org/10.1038/nature07439