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Angiotensin type 1a receptors in the forebrain subfornical organ facilitate leptin-induced weight loss through brown adipose tissue thermogenesis

OBJECTIVE: Elevations in brain angiotensin-II cause increased energy expenditure and a lean phenotype. Interestingly, the metabolic effects of increased brain angiotensin-II mimic the actions of leptin, suggesting an interaction between the two systems. Here we demonstrate that angiotensin-type 1a r...

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Detalles Bibliográficos
Autores principales: Young, Colin N., Morgan, Donald A., Butler, Scott D., Rahmouni, Kamal, Gurley, Susan B., Coffman, Thomas M., Mark, Allyn L., Davisson, Robin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354922/
https://www.ncbi.nlm.nih.gov/pubmed/25830096
http://dx.doi.org/10.1016/j.molmet.2015.01.007