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Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice
OBJECTIVE: Insulin resistance can be triggered by enhanced dephosphorylation of the insulin receptor or downstream components in the insulin signaling cascade through protein tyrosine phosphatases (PTPs). Downregulating density-enhanced phosphatase-1 (DEP-1) resulted in an improved metabolic status...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354926/ https://www.ncbi.nlm.nih.gov/pubmed/25830095 http://dx.doi.org/10.1016/j.molmet.2015.02.001 |