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Application of Design of Experiment and Simulation Methods to Liquid Chromatography Analysis of Topical HIV Microbicides Stampidine and HI443

This study intended to determine if experimental design and Monte Carlo simulation methods can be utilized to optimize the liquid chromatography (LC) analysis of active molecules. The method was applied for the simultaneous analysis of two topical microbicides, stampidine (STP) and HI443 in bulk and...

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Detalles Bibliográficos
Autores principales: Agrahari, Vivek, Meng, Jianing, Zhang, Tao, Youan, Bi-Botti C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354943/
https://www.ncbi.nlm.nih.gov/pubmed/25767739
http://dx.doi.org/10.4172/2155-9872.1000180